學術簡曆
邢秀梅,太阳集团1088vip衛生毒理系副教授,博士生導師。太阳集团app首页衛生毒理學博士,美國馬裡蘭大學藥學院博士後。長期緻力于職業與環境有害因素的毒性作用與機制研究。主持國家自然科學基金面上2項、青年項目1項。在國内外期刊上參與發表論文30餘篇,以第一、通訊(含共同)作者在Environment International、Environmental Pollution、Archives of Toxicology、Aquatic Toxicology、Toxicology and Applied Pharmacology等雜志發表SCI論著。獲得科研和教學相關獎勵10餘項、國家發明專利3項,參編專著5部。
主持項目
- 國家自然科學基金面上項目,煙酰胺單核苷酸對低濃度苯暴露緻血液毒性的幹預作用,82473670,研究期限2025.01-2028.12,主持
- 國家自然科學基金面上項目,脂肪組織對苯的ADME及其血液毒性的影響和機制研究,81973076,研究期限2020.01-2023.12,主持
- 國家自然科學基金青年項目,組蛋白修飾介導職業暴露多環芳烴早期損傷效應機制研究,81402715,研究期限2015.01-2017.12主持
- 高校基本科研業務費太阳集团app首页青年教師培育項目(研究期限:2014-2017)
- 環境污染與疾病監控教育部重點實驗室(貴州醫科大學)開放項目(2018-2020)
- 太阳集团app首页實驗室開放基金項目(指導老師,2016-2017)
參與項目
作為主要成員參與國家級項目10餘項
近年來發表的主要期刊論文(#第一作者,* 通訊作者)
Lv Y#, Li Z, Chen Y, Qin F, Liao Q, Zhang Z, Deng Q, Liu Q, Long Z, Wang Q, Chen W, Xiao Y, Xing X*. miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity. Arch Toxicol, 2025 Feb; 99(2): 717-728.
Lan X#, Huang H#, Liu J#, Zhao J, Li G, Zuo M, Xing X*, Ren X*. Compromised very-low density lipoprotein induced polyunsaturated triglyceride accumulation in N-nitrosodiethylamine-induced hepatic steatosis. Food Chem Toxicol. 2024 Apr;186:114519.
Yang R#, Zhang J#, Xing X#, Zhong S, Li W, Wen L, Zhang Y, Zhou H, Chen S, Chen W, Xiao Y, Chen L*. The involvement of nicotinate and nicotinamide metabolism pathway in attenuating benzene-induced mouse hematotoxicity. Ecotoxicol Environ Saf. 2024 Dec;288:117388.
Lizhu Ye# , Xinhang Jiang#, Liping Chen, Shen Chen, Huiyao Li , Rui Du, Wei You, Jing Peng, Ping Guo, Rui Zhang, Hongyao Yu, Guanghui Dong, Daochuan Li, Xue Li, Wen Chen , Xiumei Xing*, Yongmei Xiao*.Moderate body lipid accumulation in mice attenuated benzene-induced hematotoxicity via acceleration of benzene metabolism and clearance. Environ Int. 2023 Aug; 178: 108113.
Yan Zhang #, Yan Liu, Zongxin Li, Xin Liu, Qingfei Chen, Jingyao Qin, Qilong Liao, Rui Du, Qifei Deng, Yongmei Xiao, Xiumei Xing*. Effects of coexposure to noise and mixture of toluene, ethylbenzene, xylene, and styrene (TEXS) on hearing loss in petrochemical workers of southern China. Environ Sci Pollut Res. 2023 Mar;30(11):31620-31630.
Ying Cui#, Ziying Mo#, Penglei Ji, Jingyi Zhong, Zongxin Li, Daochuan Li, Lina Qin, Qilong Liao, Zhini He, Wei Guo, Liping Chen, Qing Wang, Guanghui Dong, Wen Chen, Yongmei Xiao, Xiumei Xing*. Benzene Exposure Leads to Lipodystrophy and Alters Endocrine Activity In Vivo and In Vitro. Front Endocrinol (Lausanne).2022,13:937281.
- Zhengbao Zhang#, Xiumei Xing#, Shuyun Jiang, Chunfang Qiu, Ziying Mo, Shen Chen, Liping Chen, Qing Wang, Yongmei Xiao, Guanghui Dong, Yuxin Zheng, Wen Chen, Daochuan Li*. Global H3K79 di-methylation mediates DNA damage response to PAH exposure in Chinese coke oven workers. Environ Pollut. 2021 Jan 1;268(Pt B):115956.
- Xiumei Xing#, Zhini He#, Ziwei Wang, Ziying Mo, Liping Chen, Boyi Yang, Zhengbao Zhang, Shen Chen, Lizhu Ye, Rui Zhang, Yuxin Zheng, Wen Chen, Daochuan Li*. Association between H3K36me3 modification and methylation of LINE-1 and MGMT in peripheral blood lymphocytes of PAH-exposed workers. Toxicol Res (Camb), 2020, 9(5):661-668.
- Xiumei Xing#, Liwen Hu#, Yuming Guo#, Michael S. Bloom, Shanshan Li, Gongbo Chen, Steve Hung Lam Yim, Namratha Gurram, Mo Yang, Xiang Xiao, Shuli Xu, Qi Wei, Hongyao Yu, Boyi Yang, Xiaowen Zeng, Wen Chen, Qiang Hu*, Guanghui Dong*. Interactions between ambient air pollution and obesity on lung function in children: The Seven Northeastern Chinese Cities (SNEC) Study. Science of the Total Environment, 2020, 699:134397.
- Zhini He#, Rui Zhang#, Shen Chen, Liping Chen, Huiyao Li, Lizhu Ye, Qiong Li, Ziwei Wang, Qing Wang, Huawei Duan, Yong Niu, Yongmei Xiao, Guanghui Dong, Daochuan Li, Dianke Yu, Yuxin Zheng, Xiumei Xing*, Wen Chen. FLT1 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation. Environ Pollut. 2019, 252 (Pt A):607-615.
- Xiumei Xing#, Jianmeng Kang, Jiahuang Qiu, Xiali Zhong, Xiongjie Shi, Bingsheng Zhou, Yanhong Wei*.Waterborne exposure to low concentrations of BDE-47 impedes early vascular development in zebrafish embryos/larvae. Aquat Toxicol. 2018, 203:19-27.
- Jie Li#, Xiumei Xing#, Xinjie Zhang#, Boxuan Liang , Zhini He, Chen Gao,Shan Wang , Fangping Wang, Haiyan Zhang, Shan Zeng , Junling Fan, Liping Chen, Zhengbao Zhang, Bo Zhang , Caixia Liu, Qing Wang, Weiwei Lin, Guanghui Dong, Huanwen Tang, Wen Chen, Yongmei Xiao, Daochuan Li*, Enhanced H3K4me3 modifications are involved in the transactivation of DNA damage responsive genes in workers exposed to low-level benzene, Environ Pollut. 2018, 234:127-135.
- Chen Gao#, Xiumei Xing#, Zhini He, Shen Chen, Shan Wang, Qingye Li, Ping Guo, Haiyan Zhang, Huiyao Li, Liping Chen, Qing Wang, Jian Zhao, Yongmei Xiao, Wen Chen*, Daochuan Li*, Hypermethylation of PGCP gene is associated with human bronchial epithelial cells immortalization, Gene, 2018, 642: 505-512.
- 莫子穎#,肖勇梅,邢秀梅*. 職業接觸甲苯暴露生物标志物研究進展.職業與健康雜志, 2021,37(6) :855-864.
發明專利
參與獲得國家發明專利2項:ZL 2015 1 0450018.6;ZL 2010 1 0255674.8
慕課建設
課程名稱: 《毒理學之曆史案例分析》 課程負責人
慕課學習平台:學堂在線、粵港澳大灣區高校在線開放課程聯盟、太阳集团app首页在線教學平台
學術專著
- 《現代毒理學》,參編第三十五章模式生物及其在毒理學中的應用; ISBN:978-7-117-26011-4/R.26012
- 《機制毒理學》,參編第二章機制毒理學研究的實驗模型;ISBN:978-7-03-066806-6
獲獎情況
- 中國毒理學會第十次全國毒理學大會報告 優秀論文
- 太阳集团1088vip2023年教師教學競賽 一等獎
- 太阳集团app首页2024年優秀碩士畢業生(指導老師)
- 中華預防醫學會科技獎(參與) 二等獎
- 中國健康科普大賽(廣東省賽區) 三等獎(指導老師)
- 太阳集团1088vip2019年度優秀個人
- 第十屆中國科協年會優秀論文(參與) 二等獎
- 湖南省第十三屆自然科學優秀學術論文(參與) 三等獎
招生類别與專業
衛生毒理學 碩士/博士
公共衛生碩士(MPH)
聯系方式
地址:廣州市中山二路74号大院 太阳集团1088vip(郵編510080)