個人簡曆 [Biography]

林華亮，教授、博導，擔任院長助理、流行病學系主任、教育部環境與健康國際合作聯合實驗室副主任。先後獲得太阳集团app首页“百人計劃”中青年傑出人才、廣東省傑出青年醫學人才等稱号，入選“全球頂尖前10萬科學家排名榜”和全球前2%頂尖科學家榜單。長期從事環境因素及其與基因易感性交互作用在慢性病發生發展中的作用和機制研究，并提出了制定大氣污染控制濃度阈值的新方法。主持國家重點研發計劃項目課題1項、國家自然科學基金4項、廣東省科技廳項目3項。擔任Green Health主編，Journal of Gerontology: Medical Sciences副主編， Environment International、Cardiac and Cardiovascular Research和The Innovation等雜志編委。以第一/通訊作者在BMJ、Journal of Hepatology、Lancet Public Health、EHP、The Innovation、American Journal of Epidemiology、EClinicalMedicine、Lancet Regional Health - Western Pacific、PLOS Medicine、Journal of Allergy & Clinical Immunology、Brain、Thorax等國際權威期刊發表學術論文100餘篇；6篇為ESI高被引論文(Top1%)，文章被引用超過15000次，H-Index達到56。獲得國家發明專利授權1項。主編中文專著4部、英文專著1部。

 

 

Hualiang Lin, Professor, Assistant Dean and Chair of Department of Epidemiology, School of Public Health, Sun Yat-sen University. He has granted Outstanding Young and Middle-aged Talents of Sun Yat-sen University's "One Hundred People Program" and Outstanding Young Medical Talents in Guangdong Province, and has been ranked as "Global Top 100,000 Scientists" and the World's Top 2% Scientists. His research focuses on the role and mechanism of environmental factors and their interaction with genetic susceptibility in the development of chronic diseases, and proposed a new method for formulating the concentration threshold of atmospheric pollution control. As the PI, he has been funded by the National Key Research and Development Plan, four projects of the National Natural Science Foundation, and three projects of Guangdong Science and Technology Department. He serves as the Editor-in-Chief of Green Health, Associate Editor of Journal of Gerontology: Medical Sciences, and editorial board member of Environment International, Cardiac and Cardiovascular Research and The Innovation. He has published more than 100 articles, such as BMJ, Lancet Public Health, Journal of Hepatology, EHP, American Journal of Epidemiology, The Innovation, EClinicalMedicine, Lancet Regional Health - Western Pacific, PLOS Medicine, Journal of Allergy & Clinical Immunology,  Brain and Thorax; eight articles are ESI Highly Cited Papers (Top1%). His study has been cited for more than 15,000 times with an H-Index of 56. He also published, as one chief editor, four monographs.




學習經曆 [Education]

  • 博士，香港中文大學賽馬會公共衛生及基層醫療學院，公共衛生

PhD, JC School of Public Health and Primary Care, The Chinese University of Hong Kong

  • 碩士，中國疾病預防控制中心，流行病與衛生統計學

Master in Epidemiology and Medical Statistics, Chinese Center for Disease Control and Prevention, China

  • 學士，山東大學太阳集团1088vip，預防醫學

Bachelor in Preventive Medicine, School of Public Health, Shandong University, China

 

工作經曆 [Employment]

  • 2021.02-至今，太阳集团1088vip, 教授、博士生導師；

2021.02-, Professor, School of Public Health, Sun Yat-sen University;

  • 2017.11-2021.02，太阳集团1088vip, 副教授、博士生導師；

2017.11-2021.02, Associate Professor, School of Public Health, Sun Yat-sen University;

  • 2015.12-2016.12，美國聖路易斯大學，訪問學者；

2015.12-2016.12, Visiting scholar, Saint Louis University, US;

  • 2012.11-2017.11，廣東省公共衛生研究院，環境與健康研究室負責人, 副主任醫師；

2012.11-2017.11, Director of Division of Environmental and Health, Guangdong Provincial Institute of Public Health;

  • 2011.10-2012.10，香港中文大學賽馬會公共衛生及基層醫療學院, 博士後；

2011.10-2012.10, Postdoctoral fellow, JC School of Public Health and Primary Care, The Chinese University of Hong Kong;

  • 2007.07-2008.09，深圳出入境檢驗檢疫局, 國際旅行衛生保健中心

2007.07-2008.09, International Travel Health Care Center, Shenzhen Entry Exit Inspection and Quarantine Bureau, China


社會兼職 [Memberships]

  • 中華預防醫學會流行病學委員會 委員

Committee Member, Epidemiology Branch of Chinese Preventive Medicine Association

  • 中華預防醫學會環境衛生學委員會 委員

Committee Member, Environmental Health Branch of Chinese Preventive Medicine Association

  • 中華預防醫學會殘疾預防與控制委員會 委員

Committee Member, Specialist Committee of Disability Prevention and Control of Chinese Preventive Medicine Association

  • 中國初級衛生保健基金會醫學統計專業委員會 常務委員

Standing Committee, Specialist Committee of Medical Statistics of Primary Health Care Foundation of China

  • 中華預防醫學會媒介生物學及控制委員會 委員

Committee Member, Vector Biology and Control Branch of Chinese Preventive Medicine Association

  • 廣東省精準醫學應用學會腦卒中分會 副主任委員

Deputy Director, Stroke Branch of Guangdong Precision Medicine Application Association

  • 廣東省精準醫學應用學會頭痛分會 副主任委員

Deputy Director, Headache Branch of Guangdong Precision Medicine Application Association

  • 廣東省預防醫學會流行病學青年委員會 副主任委員

Deputy Director, the Youth Committee on Epidemiology of Guangdong Preventive Medicine Association

  • Green Health雜志 主編

Editor in Chief, Green Health

  • Journal of Gerontology: Medical Sciences雜志副主編

Associate Editor, Journal of Gerontology: Medical Sciences

  • Cardiac and Cardiovascular Research雜志 編委

Member of the Editorial Board, Cardiac and Cardiovascular Research

  • Environment International 雜志 編委

Member of the Editorial Board, Environment International

  • The Innovation雜志 編委

Member of the Editorial Board, The Innovation

  • Future雜志 編委

Member of the Editorial Board, Future

  • 華南預防醫學雜志編委

Member of the Editorial Board, South China Journal of Preventive Medicine

 

承擔或參與的主要課題 [Research projects]

    1. 國家重點研發計劃課題，2022YFC2305305,整合病原基因組和多源異構環境數據的急性傳染病預警模型研究，2022/12-2025/11,課題負責人；

State Key Research and Development Program of China (2022YFC2305305), Research on the early warning model of acute infectious diseases integrating pathogenic genome and multi-source heterogeneous environmental data. 2022/12-2025/11, PI2

    2. 國家自然科學基金面上項目，81972993，孕期細顆粒物暴露對新生兒早産風險的影響及胎盤外泌體介導的miRNA-21和miRNA-200a對其調控機制研究，2020/01–2023/12，主持;

National Natural Science Foundation of China (81972993) Research on the effect of exposure to fine particles during pregnancy on the risk of premature birth in newborns and the regulatory mechanism of miRNA-21 and miRNA-200a mediated by placental exocrine. 2020/01–2023/12, PI.

   3. 國家自然科學基金新冠肺炎專項項目，82041021，人口流動及其幹預措施對新冠肺炎在湖北省内和跨省傳播的驅動作用、機制和影響因素研究，2020/03–2022/03，主持;

National Natural Science Foundation of China (82041021) Research on the driving role, mechanism and influencing factors of population flow and its intervention measures on the spread of COVID-19 in Hubei Province and across provinces. 2020/03–2022/03, PI.

   4. 國家自然科學基金面上項目，82373534 ，血清miR-200a-SLC7A11介導細胞鐵死亡在大氣黑碳緻腦卒中發病中的作用及機制研究，2024/01–2027/12，主持;

National Natural Science Foundation of China (82373534 ), Study on the role and mechanism of cell iron death mediated by serum miR-200a-SLC7A11 in the incidence of cerebral stroke caused by atmospheric black carbon. 2024/01–2027/12, PI.

   5. 比爾及梅琳達·蓋茨基金會項目，社會環境因素對呼吸系統疾病時空傳播的影響及其機制研究，2020-2022，主持；

Bill & Melinda Gates Foundation, Research on the influence of social and environmental factors on the space-time transmission of respiratory diseases and its mechanism. 2020-2022, PI.

   6. 中央高校青年教師重點培育項目，19ykzd16，孕期空氣污染暴露與早産的流行病學和機制研究，2019/01–2021/12，主持;

Key training projects for young teachers in central colleges and universities (19ykzd16), Epidemiological and mechanism research on the relationship between air pollution exposure during pregnancy and premature birth. 2019/01–2021/12, PI.

    7. 廣東省自然科學基金面上項目，孕期臭氧暴露對新生兒早産發生風險的影響及其機制研究，2022-2024，主持；

Natural Science Foundation of Guangdong Province, Research on the impact of ozone exposure during pregnancy on the risk of premature birth in newborns and its mechanism. 2022-2024, PI.

   8. 廣東省自然科學基金面上項目，炎症通路在孕期大氣污染物暴露緻新生兒早産發生風險中的影響及機制研究，2024-2026，主持；

Natural Science Foundation of Guangdong Province, Research on the influence and mechanism of inflammatory pathways on the risk of premature birth of newborns due to exposure to atmospheric pollutants during pregnancy. 2024-2026, PI.

   9. 廣東省科技廳“海外名師”團隊項目，基于人群健康效應分析的粵港地區大氣環境質量标準制修訂，2021/09–2023/08，主持;

Science and Technology Planning Project of Guangdong, Revision of the atmospheric environmental quality standard system in Guangdong and Hong Kong based on the analysis of population health effects. 2021/09–2023/08, PI.

   10. 國家自然科學基金青年項目，81202176，宣威市肺癌的時空演變及其影響因素研究，2013/01–2015/12，主持;

National Natural Science Foundation of China (81202176), Research on the space-time evolution of lung cancer in Xuanwei City and its influencing factors. 2013/01–2015/12, PI.

   11. 國家科技部重點研發計劃，氣候變化健康風險評估、早期信号捕捉及應對策略研究，2018-2023，課題一項目骨幹。

State Key Research and Development Program of China, Research on health risk assessment, early signal capture and coping strategies related to climate change. 2018-2023, participation.

   12. 國家自然科學基金面上基金項目，81273139，粵港兩地登革熱暴發媒介伊蚊密度阈值研究，2013/01–2016/12，參與;

National Natural Science Foundation of China (81273139) Research on the density threshold of Aedes mosquitoes, the medium of dengue fever outbreak in Guangdong and Hong Kong. 2013/01–2016/12, participation.

   13. 國家自然科學基金面上基金項目，30771873，我國登革熱的風險評估研究，2008/01–2008/12，參與。

National Natural Science Foundation of China (30771873), Research on the risk assessment of dengue fever in China. 2008/01–2008/12, participation.

 

代表文章 (*通訊作者) [Publications (*Corresponding author)] 

  1. Ran S, Zhang J, Tian F, Qian Z, Wei S, Wang Y, Chen G, Zhang J, Arnold LD, McMillin SE, Lin HL*. Association of metabolic signatures of air pollution with MASLD: Observational and Mendelian randomization study. Journal of Hepatology, 2025;82(4): 560-570.
  2. Chen G, Qian ZM, Zhang J, Wang X, Zhang Z, Cai M, Arnold LD, Abresch C, Wang C, Liu Y, Fan Q, Lin HL*. Associations between Changes in Exposure to Air Pollutants due to Relocation and the Incidence of 14 Major Disease Categories and All-Cause Mortality: A Natural Experiment Study. Environmental Health Perspectives. 2024;132(9):97012.
  3. Zhuo B, Ran S, Qian AM, Zhang J, Tabet M, Howard SW, Zhang Z, Tian F, Lin HL*. Air Pollution Metabolomic Signatures and Chronic Respiratory Diseases Risk: A Longitudinal Study. Chest. 2024, 166(5): 975-986.
  4. Tian F, Wang Y, Qian Z, Ran S, Zhang Z, Wang C, McMillin SE, Chavan NR, Lin HL*. Plasma metabolomic signature of healthy lifestyle, structural brain reserve and risk of dementia. Brain. 2024;148(1):143-53.
  5. Tian F, Wang Y, Wei S, Zhang C, Wu G, Zhang Z, Ai B, Wang X, Wang C, Lin HL*. Post-cardiovascular disease healthy lifestyle, inflammation and metabolic biomarkers, and risk of dementia: a population-based longitudinal study. The American Journal of Clinical Nutrition. 2025;121(3):511-21.
  6. Hu P, Shen L, Chen G, Yang W, Ji Y, He B, Lin HL*. Long-term exposure to fine particulate matter constituents and the prognosis of oral cancer patients: A prospective study in Southeastern China. Journal of Hazardous Materials. 2025;487: 137304.
  7. Qi J, Ruan Z, Qian ZM, Yin P, Yang Y, Acharya BK, Wang L, Lin HL*, Potential gains in life expectancy by attaining daily ambient fine particulate matter pollution standards in mainland China: A modeling study based on nationwide data. PLOS Medicine, 2020, 17(1):e1003027 (ESI高被引論文，ESI Highly Cited Paper).
  8. Ma Q, Li R, Wang L, Yin P, Wang Y, Yan C, Ren Y, Qian ZM, Vaughn MG, McMillin SE, Hay SI, Naghavi M, Cai M, Wang C, Zhang Z, Zhou M*, Lin HL*, Yang Y*. Temporal trend and attributable risk factors of stroke burden in China, 1990-2019: An analysis for the Global Burden of Disease study 2019. The Lancet Public Health. 2021, 6 (12): e897-e906 (ESI高被引和熱點論文，ESI Highly Cited Paper and Hot Paper).
  9. Zhang Z, Chen L, Wang X, Wang C, Yang Y, Li H, Cai M, Lin HL*. Associations of Air Pollution and Genetic Risk With Incident Dementia: A Prospective Cohort Study. American Journal of Epidemiology. 2023;192(2):182-94.
  10. Zhang J, Chen G, Xia H, Wang X, Wang C, Cai M, Gao Y, Lip GYH, Lin HL*. Associations of Life’s Essential 8 and fine particulate matter pollution with the incidence of atrial fibrillation. Journal of Hazardous Materials. 2023; 459: 132114.
  11. Wang X, Guo Y, Cai M, Qian Z, Zhang S, Zhang Z, Yang Y, Vaughn MG, Aaron HE, Wu F, Zhang Y, Lin HL*. Constituents of fine particulate matter and asthma in six low- and middle-income countries. Journal of Allergy and Clinical Immunology. 2022. 150: 214-222.
  12. Cai M, Zhang S, Lin X, Qian Z, McMillin SE, Yang Y, Zhang Z, Pan J, Lin HL*, Association of Ambient Particulate Matter Pollution of Different Sizes with In-Hospital Case Fatality Among Stroke Patients in China. Neurology, 2022. 98(24): e2474-e2486 (ESI高被引論文，ESI Highly Cited Paper).
  13. Cai M, Lin X, Wang X, Zhang S, Wang C, Zhang Z, Pan J, Lin HL*, Long-term exposure to ambient fine particulate matter chemical composition and in-hospital case fatality among patients with stroke in China. Lancet Regional Health - Western Pacific 2023:100679 (ESI高被引論文，ESI Highly Cited Paper).
  14. Zhang S, Qian Zhengmin M, Chen L, Zhao X, Cai M, Wang C, Zou H, Wu Y, Zhang Z, Li H, Lin HL*. Exposure to Air Pollution during Pre-Hypertension and Subsequent Hypertension, Cardiovascular Disease, and Death: A Trajectory Analysis of the UK Biobank Cohort. Environmental Health Perspectives. 2023;131(1):017008 (ESI高被引論文，ESI Highly Cited Paper).
  15. Cai M, Li H, Wu Y, Zhang S, Wang X, Zhang Z, Lin HL*, Ambient Air Pollution Associated with Body Fat Percentages at Different Body Compartments: A Cohort Study of UK Biobank Participants. Environmental Health Perspectives, 2022. 130(6): 067702.
  16. Chen L, Cai M, Li H, Wang X, Tian F, Wu Y, Zhang Z, Lin HL*, Risk/benefit tradeoff of habitual physical activity and air pollution on chronic pulmonary obstructive disease: findings from a large prospective cohort study. BMC Medicine, 2022. 20(1): 70 (ESI高被引論文，ESI Highly Cited Paper).
  17. Tian F, Cai M, Li H, Qian Z, Chen L, Zou H, Zhang Z, Wang C, Xian H, McMillin SE, Lin HL*. Air Pollution Associated With Incident Stroke, Poststroke Cardiovascular Events, and Death: A Trajectory Analysis of a Prospective Cohort. Neurology. 2022;99(22):e2474-e2484.
  18. Cao D, Li D, Wu Y, Qian ZM, Liu Y, Liu Q, Sun J, Guo Y, Zhang S, Jiao G, Yang X, Wang C, McMillin SE, Zhang X, Lin HL*. Ambient PM2.5 exposure and hospital cost and length of hospital stay for respiratory diseases in 11 cities in Shanxi Province, China. Thorax, 2021, 76:815–820.
  19. Liu K, Ai S, Song S, Zhu G, Tian F, Li H, Gao Y, Wu Y, Zhang S, Shao Z, Liu Q, Lin HL*, Population movement, city closure in Wuhan and geographical expansion of the 2019-nCoV pneumonia infection in China in January 2020. Clinical Infectious Diseases, 2020, 71(16): 2045-2051.
  20. Ruan Z, Qi J, Qian ZM, Zhou M, Yang Y, Zhang S, Vaughn MG, LeBaige MH, Yin P, Lin HL*. Disease burden and attributable risk factors of respiratory infections in China from 1990 to 2019.  Lancet Regional Health - Western Pacific, 2021, 11(2021): 100153.
  21. Wang HL, Sun J, Qian ZM, Gong YQ, Zhong JB, Yang RD, Wan CL, Zhang SQ, Ning DF, Xian H, Chang JJ, Wang CJ, Shacham E, Wang JQ, Lin HL*. Association between Air Pollution and Atopic Dermatitis in Guangzhou, China: Modification by Age and Season. British Journal of Dermatology, 2021, 184(6): 1068-1076.
  22. Zhang Z, Chen L, Qian Z, Li H, Cai M, Wang X, McMillin SE, Vaughn MG, Liu K, Shao Z, Lin HL*. Residential green and blue space associated with lower risk of adult-onset inflammatory bowel disease: Findings from a large prospective cohort study. Environment International. 2022;160: 107084.
  23. Tian F, Liu X, Chao Q, Qian Z, Zhang S, Qi L, Niu Y, Arnold LD, Zhang S, Li H, Lin HL*, Liu QY*. Ambient air pollution and low temperature associated with case fatality of COVID-19: A nationwide retrospective cohort study in China. The Innovation. 2021, 2(3): 100139
  24. Wu R, Ai S, Cai J, Zhang S, Qian Z, Zhang Y, Wu Y, Chen L, Tian F, Li H, Li M, Lin HL*. Predictive model and risk factors for case fatality of COVID-19: a cohort of 21,392 cases in Hubei, China. The Innovation, 2020, 1(2): 100022.
  25. Yang Y, Qi J, Ruan Z, Yin P, Zhang S, Liu J, Liu Y, Li R, Wang L, Lin HL*. Changes in life expectancy of respiratory diseases from attaining daily PM2.5 standard in China: A nationwide observational study. The Innovation, 2020, 1(3): 100064.
  26. Zhang S, Yang Y, Xie X, Li H, Han R, Hou J, Sun J, Qian Z, Wu S, Huang C, Howard SW, Tian F, Deng W, Lin HL*. The effect of temperature on cause-specific mental disorders in three subtropical cities: A case-crossover study in China. Environment International, 2020, 143: 105938.
  27. Tian F, Qi J, Wang L, Yin P, Qian Z, Ruan Z, Liu J, Liu Y, McMillin SE, Wang C, Lin HL*, Zhou M*. Differentiating the effects of ambient fine and coarse particles on mortality from cardiopulmonary diseases: A nationwide multicity study. Environment International, 2020, 145: 106096.
  28. Liang Z, Yang Y, Qian Z, Ruan Z, Chang J, Vaughn MG, Zhao Q, Lin HL*, Ambient PM2.5 and birth outcomes: Estimating the association and attributable risk using a birth cohort study in nine Chinese cities. Environment International, 2019, 126:329-335.
  29. Ruan Z, Qian ZM, Xu Y, Wu J, Kan H, Yang Y, Acharya BK, Jiang C, Syberg KM, Iwelunmor J, Ma W, Lin HL*, Applying the concept of "number needed to treat" to the formulation of daily ambient air quality standards. Chemosphere 2019, 222: 665-670.

 

研究生招生與博士後招聘 [Enrollment and Recruitment]

  • 碩士研究生(方向：流行病學)

Master (Direction: Epidemiology)

  • 博士研究生(方向：流行病學)

Ph.D. (Direction: Epidemiology)

  • 博士後 名額不限(方向：流行病學、環境流行病學或相關學科) 

Postdoctor, Quota: No limitation (Direction: Epidemiology, Environmental Epidemiology or related disciplines)

 

獲獎情況 [Awards]

  • 2024年，廣東省科技廳科普作品創作大賽優秀指導老師

The Science Popularization and Creation Competition of Guangdong Provincial Department of Science and Technology in 2024, Excellent Instructor

  • 2023、2024年，全國大學生基礎醫學創新研究暨實驗設計論壇金獎、最佳學術獎 優秀指導老師

The National Forum for Undergraduate on Innovation Research & Experimental Design Competition in 2023 & 2024, Excellent Instructor of the Gold Award and Best Academic Award

  • 2023年，中國大學生統計建模大賽研究生組全國二等獎 優秀指導老師

The National College Student Statistical Modeling Competition in 2023, Excellent Instructor of the National Second Prize in postgraduate group

  • 2022年，全國健康科普大賽全國二等獎 優秀指導老師

The National Health Science Popularization Competition in 2022, Excellent Instructor of the National Second Prize

  • 2022年，中國大學生統計建模大賽本科組全國二等獎 優秀指導老師

The National College Student Statistical Modeling Competition in 2022, Excellent Instructor of the National Second Prize in undergraduate group

  • 2022年，廣東省大學生統計建模大賽一等獎 優秀指導老師

College Student Statistical Modeling Competition of Guangdong Province in 2022, Excellent Instructor of the First Prize

  • 2017年，太阳集团app首页“百人計劃”中青年傑出人才

"One Hundred People Plan" of Sun Yat-sen University in 2017, Outstanding young and middle-aged talents

  • 2018年，廣東省傑出青年醫學人才稱号

Outstanding Young Medical Talents in Guangdong Province in 2018