【學習和工作經曆】
- 2021/05- 太阳集团app首页 醫學統計學系 副教授、博士生導師
- 2017/07-2021/03 紐約州立大學UAlbany 博士後
- 2012/09-2017/06 太阳集团app首页 醫學統計學系 碩博連讀
- 2007/09-2012/06 甯波大學 醫學部 本科
【個人概述】
醫學統計學系副教授、博士生導師,主要研究方向為因果推斷和因果中介分析方法改進及應用。主持國自然、廣東省自然、廣州市科技局項目等;以第一或通訊作者發表SCI論文60多篇,被引>3000,H-index=31;研究成果受到路透社(Reuters)、CNN、國會山報(the Hill)等國際知名媒體的報道和國際同行的高度評價。入選太阳集团app首页“百人計劃”人才引進項目(2021)、廣東省“珠江人才計劃”青年拔尖人才項目(2022)、中國科協“青年人才托舉工程”項目(2023)等。此外擔任全國公共衛生與預防醫學名詞編寫委員會秘書、廣東省“百千萬工程”衛生健康領域專家庫成員、中華預防醫學會繼續教育分會青年委員組組長、廣東省預防醫學會健康醫療大數據專業委員會委員,此外擔任《Research》、《新醫學》、《華南預防醫學》等期刊青年編委等。
【主要課題方向】
- 基于觀察性數據的因果推斷方法改進。
- 混合暴露健康因果效應評估方法改進。
- 因果中介分析方法改進。
基于因果推斷及因果中介分析方法的環境暴露健康效應研究。
*博士生課題以統計方法學改進為主,碩士和博士後課題根據前期背景商定。歡迎感興趣的同學來郵咨詢~
【研究項目】
- 2025/01-2027/12 加權非線性因果推斷模型構建及其在環境混合暴露的心血管健康效應評估中的應用,廣東省自然科學基金面上項目(2025A1515012021),主持
- 2024/01-2024/12 Multivariate Statistical Methods多變量統計分析方法,研究生全英文核心課程建設項目(2024_02300_B24743),主持
- 2023/01-2025/12 氣象因素和大氣污染的心肺健康因果效應評估及時空因果推斷模型研究,國家自然科學基金青年項目(82204162),主持
- 2023/04-2025/03 環境暴露的社區易感性指數的構建研究,廣州市科技局(2023A04J2072),主持
- 2022/01-2024/12 氣象與細顆粒物的交互作用對血脂代謝的影響及其易感因素和機制初探,廣東省自然科學基金面上項目(2022A1515010823),主持
- 2023/01-2023/12 基于因果中介推斷的“綠地暴露-空氣污染-心血管疾病”路徑探索研究,高校基本科研業務費青年教師培育項目(23qnpy108),主持
- 2018/02-2022/01 Assess and model the health effects, population, and infrastructural vulnerabilities of power outage, 美國國立衛生研究院(NIH),統計負責人
- 2019/10-2023/09 Evaluating short-/long-term impacts and exposure sources of ultrafine particles on multiple health outcomes in New York State by using high-resolution pollutant simulations,紐約州能源研究與發展部門(NYSERDA),統計負責人(2019/10-2021/03)
- 2017/07-2018/12 Impact of environmental policies and changes in air pollution levels, particle composition, and cause-specific hospital admission rates in New York State,紐約州能源研究與發展部門(NYSERDA),統計負責人
【部分論文列表】
- Zhang S, Chen Z, Du Z, Wang S, Chen D, Ruan X, Lin Z, Zheng Z, Li K, Chen X, Wu Z, Qin Q, Zhang M, Zhu S, Wu S, Zeng F, Wang Y#, Zhang W#. The causal links between long-term exposure to major chemical components of PM2.5 and overall outpatient visits in mainland China: A nationwide study in the difference-in-differences framework. Journal of Advanced Research (2025). 2025 Mar 2:S2090-1232(25)00139-0. https://doi.org/10.1016/j.jare.2025.02.041.
- Zhang Y, Wei J, Chen S, Benmarhnia T, Zhang K, Wang X, Deng X, Gu H, Lin Z, Qu Y, Xiao J, Jiang J, Du Z#, Zhang W#, Hao Y#. Individual and mixed associations between fine particulate matter components and hospital admissions for hypertension: insights from a large-scale South Chinese cohort study. Sustainable Cities and Society (2025), 106293. DOI: https://doi.org/10.1016/j.scs.2025.106293.
- Wu G., Wang S., Wu W., Benmarhnia T., Lin S., Zhang K., Romeiko X., Gu H., Qu Y., Xiao J., Deng X., Lin Z., Du Z.#, Zhang W.#, Hao Y#. Potential causal links of long-term PM2.5 components exposure with diabetes incidence and mortality in the United States. Sustainable Cities and Society (2025), 106071. https://doi.org/10.1016/j.scs.2024.106071
- Li, Z., Wu, W., Huang, Y., Lawrence, W. R., Lin, S., Du, Z., Wang, Y., Hu, S., Hao, Y., & Zhang, W.#. Urban Residential Greenness and Cancer Mortality: Evaluating the Causal Mediation Role of Air Pollution in a Large Cohort. Environmental Pollution (2024), 124704. https://doi.org/10.1016/j.envpol.2024.124704
- Zhang, Y., Chen, S., Wei, J., Jiang, J., Lin, X., Wang, Y., Hao, C., Wu, W., Yuan, Z., Sun, J., Wang, H., Du, Z.#, Zhang, W.#, & Hao, Y.#, Long-term PM1 exposure and hypertension hospitalization: A causal inference study on a large community-based cohort in South China. Science Bulletin (2024). https://doi.org/10.1016/j.scib.2024.03.028
- Li, Z., Wang, Y., Wu, W., Zhao, Y., Wang, S., Wang, P., Lin, X., Gong, Y., Wu, Z., Li, X., Sun, J., Zhao, N., Huang, Y.#, Hu, S.#, & Zhang, W.#, The relative contribution of PM2.5 components to the obstructive ventilatory dysfunction—insights from a large ventilatory function examination of 305,022 workers in southern China. Environment International (2024), 187, 108721. https://doi.org/10.1016/j.envint.2024.108721
- Wu, W., Chen, D., Ruan, X., Wu, G., Deng, X., Lawrence, W., Lin, X., Li, Z., Wang, Y., Lin, Z., Zhu, S., Deng, X., Lin, Q., Hao, C., Du, Z., Wei, J.#, Zhang, W.#, Hao, Y.#, Residential greenness and chronic obstructive pulmonary disease in a large cohort in southern China: Potential causal links, risk trajectories, and mediation pathways, Journal of Advanced Research (2024), doi: https://doi.org/10.1016/j.jare.2024.05.025
- Sun X, Lin X, Yao J, Tian T, Li Z, Chen S, Hu W, Jiang J, Tang H, Cai H, Guo T, Chen X, Chen Z, Zhang M, Sun Y, Lin S, Qu Y, Deng X, Lin Z, Xia L#, Jin Y#, Zhang W.#, Potential causal links of long-term exposure to PM2.5 and its chemical components with the risk of nasopharyngeal carcinoma recurrence: A 10-year cohort study in South China. International Journal of Cancer (2024);1‐9. doi: https://doi.org/10.1002/ijc.35047
- Wang Y, Wang Z, Jiang J, Guo T, Chen S, Li Z, Yuan Z, Lin Q, Du Z, Wei J, Hao Y, Zhang W#. The Effect of Long-Term Particulate Matter Exposure on Respiratory Mortality: Cohort Study in China. JMIR Public Health Surveill (2024);10:e56059. doi: https://doi.org/10.2196/56059
- Wang, X., Zhang, Y., Tarik, B., Zhang, K., Lin, S., Deng, X., Gu, H., Wu, W., Lin, X., Du, Z., Wang, Y., Qu, Y., Lin, Z., Zhang, M., Sun, Y., Dong, G., Wei, Y.#, Zhang, W.#, & Hao, Y#. The effect of residential greenness on cardiovascular mortality from a large cohort in South China: An in-depth analysis of effect modification by multiple demographic and lifestyle characteristics. Environment International (2024), 190, 108894. https://doi.org/10.1016/j.envint.2024.108894
- Wang, S., Ma, Y., Wu, G., Du, Z., Li, J., Zhang, W.#, Hao, Y. Relationships between long-term exposure to major PM2.5 constituents and outpatient visits and hospitalizations in Guangdong, China. Environmental Pollution (2024), 123866. https://doi.org/10.1016/j.envpol.2024.123866
- Lin X, Jin Y, Yao J, Sun X, Tian T, Li Z, Chen S, Jiang J, Hu W, Hao Y#, Xia L#, Zhang W#. Adverse prognosis of nasopharyngeal carcinoma following long-term exposure to multiple air pollutants. Environmental Chemistry Letters (2023), doi: https://doi.org/10.1007/s10311-023-01659-2
- Wu, W., Wu, G., Wei, J., Lawrence, W. R., Deng, X., Zhang, Y., Chen, S., Wang, Y., Lin, X., Chen, D., Ruan, X., Lin, Q., Li, Z., Lin, Z., Hao, C., Du, Z., Zhang, W.#, & Hao, Y.#, Potential causal links and mediation pathway between urban greenness and lung cancer mortality: result from a large cohort (2009 to 2020). Sustainable Cities and Society (2023), 105079. https://doi.org/10.1016/J.SCS.2023.105079
- Guo T, Chen S, Wang Y, Zhang Y, Du Z, Wu W, Chen S, Ju X, Li Z, Jing Q, Hao Y, Zhang W#. Potential causal links of long-term air pollution with lung cancer incidence: From the perspectives of mortality and hospital admission in a large cohort study in southern China. International Journal of Cancer (2023). doi: https://doi.org/10.1002/ijc.34699
- Wang Y, Wei J, Zhang Y, Guo T, Chen S, Wu W, Chen S, Li Z, Qu Y, Xiao J, Deng X, Liu Y, Du Z#, Zhang W#, Hao Y#. Estimating causal links of long-term exposure to particulate matters with all-cause mortality in South China. Environment International (2023),171:107726. doi: https://doi.org/10.1016/j.envint.2022.107726
- Lin, X., Tian, T., Shi, C., Wang, P., Chen, S., Guo, T., Li, Z., Liang, B., Zhang, W.#, Qin, P.#, Hao, Y. What are the individual and joint impacts of key meteorological factors on the risk of unintentional injuries? A case-crossover study of over 147,800 cases from a sentinel-based surveillance system. Sustainable Cities and Society (2023), 91, 104413. https://doi.org/10.1016/J.SCS.2023.104413
- Cai H, Du Z, Lin X, Lawrence WR, Hopke PK, Rich DQ, Lin S, Xiao J, Deng X, Qu Y, Lin Z, Wang X, Ju X, Chen S, Zhang Y, Wu W, Wang Y, Gu J, Hao Y#, Zhang W#. Interactions between long-term ambient particle exposures and lifestyle on the prevalence of hypertension and diabetes: insight from a large community-based survey. Journal of Epidemiology & Community Health (2023): jech-2023-220480. doi: https://doi.org/10.1136/jech-2023-220480
- Qu Y*, Zhang W*, Boutelle AM, Ryan I, Deng X, Liu X, Lin S. Associations Between Ambient Extreme Heat Exposure and Emergency Department Visits Related to Kidney Disease. American Journal of Kidney Diseases (2022): S0272-6386(22)00918-0. doi: https://doi.org/10.1053/j.ajkd.2022.09.005
- Zhang, W.*, Gao, M.*, Xiao, X.*, Xu, S.-L., Lin, S., Wu, Q.-Z., Chen, G.-B., Yang, B.-Y., Hu, L.-W., Zeng, X.-W., Hao, Y., Dong, G.-H., Long-term PM0.1 exposure and human blood lipid metabolism: New insight from the 33-community study in China. Environmental Pollution (2022). 119171.
- Zhang W, Sheridan S, Birkhead G, Croft D, Brotzge J, Justino J, Stuart N, Du Z, Romeiko X, Ye B, Dong G, Hao Y, Lin S. Power Outage: An Ignored Risk Factor for Chronic Obstructive Pulmonary Disease Exacerbations. CHEST (2020); 158 (6): 2346-2357.
- Zhang W, Kinney P, Rich DQ, Sheridan SC, Romeiko XX, Dong G, Stern EK, Du Z, Xiao J, Lawrence WR, Lin Z, Hao Y, Lin S. How Community Vulnerability Factors Jointly Affect Multiple Health Outcomes after Catastrophic Storms. Environment International (2020); 134: 105285.
【會議報告】
- 張王劍、張昱勤、郝元濤等,考慮暴露溢出效應的時空因果推斷模型構建及應用,2024中國生物統計學術會議,廣東廣州,2024/7
- 張王劍、吳文靜、郝元濤等,綠地暴露與肺癌死亡風險間的因果效應及其中介機制研究,2023中國生物統計學術會議,山西太原,2023/7
- Zhang W, Lin S. The association between power outage and the exacerbation of Chronic Obstructive Pulmonary Disease (COPD). The 31st Annual Scientific Conference of the International Society of Environmental Epidemiology (ISEE), Utrecht, Netherlands; 2019.
- Zhang W. How Community Vulnerability Factors Jointly Affect Multiple Health Outcomes after Catastrophic Storms. Panelist at the Resilience In Sustainable rEconstruction (RISE) National Conference: Transforming University Engagement In Pre- and Post-Disaster Environments: Lessons from Puerto Rico, 11/18/2019.
- Zhang W, Lin S, Hopke P, Thurston S, Wijngaarden E van, Croft D, Squizzato S, Masiol M, Rich D. Does the Association between Cardiovascular Hospital Admissions and Fine Particle Concentrations Change Before, During, and After Implementation of Multiple Environmental Policies? The New York State Accountability Study. The 30th Annual Scientific Conference of the International Society of Environmental Epidemiology (ISEE), Ottawa, Canada; 2018.
【R軟件程序包】
- Zhang W, Du Z, Deng X, Ye Bo, Lin Z, Yao J, Jin Y, Lawrence WR, Hao Y. rSPARCS: Sites, Population, and Records Cleaning Skills. 2018. Available at https://cran.r-project.org/package=rSPARCS.
- Du Z, Zhang W, Hao Y. gamRR: Calculate the RR for the GAM. 2018. Available at https://cran.r-project.org/package=gamRR .
- Lin Z, Laska E, Siegel C, Zhang W, Lin Q, Ye B. CRWRM: Changing the Reference Group without Re-Running the Model. 2019. Available at https://CRAN.R-project.org/package=CRWRM.
- Deng X, Zhang W, Lin S. APML: An Approach for Machine-Learning Modelling. 2020. Available at https://CRAN.R-project.org/package= APML.
【參編教材與論著】
- 《衛生信息資源規劃與管理》第1版,人民衛生出版社,2023年,編委
- 《醫學統計學實習指導及習題集》第1版,人民衛生出版社,2016年,參編人員
- 《醫學統計學》第1版,北京大學醫學出版社,2013年,參編人員
【指導學生參加大創項目情況】
- 2023年,基于因果中介推斷的大氣污染物在綠地暴露和心血管疾病死亡風險之間的複雜作用分析(馬玉潔、王爽、王卓浩),國家級,入選第17屆全國大學生創新年會(2024,成都)
- 2023年,基于因果推斷和混合暴露評估方法研究長期空氣污染暴露的人群健康效應(趙丹桂、廖思萍、葉佩雯),校級
- 2022年,基于空間因果推斷的大氣污染-心血管疾病死亡風險研究(林钰純、趙延婕、陳柳府),國家級
【指導學生獲獎情況】
- 2024年,考慮暴露溢出的時空因果推斷模型構建及其在大氣顆粒物心血管健康效應評估中的應用(張昱勤),太阳集团app首页優秀博士畢業論文
- 2024年,基于因果中介分析的鄰苯二甲酸酯—血脂—心血管疾病死亡中介路徑研究(馬玉潔),太阳集团app首页優秀本科畢業論文
- 2024年,貝葉斯核機器回歸模型在大數據時代的算法優化與驗證研究(蔡歡樂、唐慧、陳丹),第十屆全國大學生統計建模大賽廣東賽區研究生組三等獎
- 2024年,基于機器學習算法的高度近視白内障手術屈光預後的預測模型構建(楊藝軒、劉麗敏、王子琳),第十屆全國大學生統計建模大賽廣東賽區本科生組三等獎
- 2023年,基于因果中介推斷的大氣污染物在綠地暴露和全因死亡風險之間的複雜作用分析(王爽、馬玉潔、王卓浩),第九屆全國大學生統計建模大賽廣東賽區本科生組一等獎、國賽三等獎
- 2023年,多環芳烴組分混合暴露對全死因死亡的因果推斷(蔡歡樂、唐慧、陳丹),第九屆全國大學生統計建模大賽廣東賽區研究生組二等獎
- 2023年,基于雙重差分法探索PM2.5及其組分對醫院門診就診量的影響研究(張率骐、鄭子涵、李坤英),第九屆全國大學生統計建模大賽廣東賽區本科生組一等獎
- 2023年,中國中老年人共病對家庭衛生經濟負擔的影響——基于因果推斷研究(陳詩敏、李知強、王旭),第九屆全國大學生統計建模大賽廣東賽區研究生組三等獎
- 2022年,基于cox邊際結構模型的時依暴露因素的因果效應估計(張昱勤、陳世瑞、郭童),第八屆全國大學生統計建模大賽廣東賽區研究生組三等獎
- 2022年,貝葉斯空間模型在中國肺結核數據分析中的應用(林钰純、陳柳府、趙延婕),第八屆全國大學生統計建模大賽廣東賽區本科生組一等獎
【社會兼職】
- 全國公共衛生與預防醫學名詞編寫委員會秘書
- 中華預防醫學會繼續教育分會青年委員組組長
- 廣東省預防醫學會健康醫療大數據專業委員會委員
- Research雜志青年編委
- 《新醫學》雜志青年編委
- 《華南預防醫學》雜志青年編委
【招生方向】
- 專業背景:數學、統計學相關專業、預防醫學等。
- 重點考察:自學和獨立解決問題的能力、數理統計知識、編程能力、溝通和協作能力、英文寫作能力。
- 歡迎專注學術的本科生、碩士、博士、博士後加入我們團隊!