學術簡曆

1999-2004年就讀于鄭州大學太阳集团1088vip，獲醫學學士學位；

2004-2010年就讀于太阳集团1088vip，獲醫學碩士和博士學位；

2011-2013年在太阳集团app首页中山醫學院做博士後研究；

2013年受聘于太阳集团1088vip任講師；

2017年被聘為副教授；

2017-2018年美國杜克大學訪問學者。

    緻力于傳染病流行病學方面的研究，入選2015年廣州市“珠江科技新星專項”人才支持項目；主持國家自然科學基金青年項目1項，中國博士後基金1項，廣東省自然科學基金1項，廣東省科技計劃1項，指導學生國家大學生創新訓練計劃項目4項；參與“十二五”“十三五”國家傳染病防治科技重大專項2項，國家自然科學基金4項。在國内外雜志發表論文81篇，以第一作者或通訊作者在Emerg Microbes Infect，Scientific reports,Epidemiology and Infection、International Journal of Infectious Diseases等雜志發表論著41篇，參與獲得發明專利3項，作為主編參編專著1部。近年來的主要研究方向是：傳染病流行規律及幹預研究，傳染病疫苗研發和評價。

社會兼職

1. 國際傳染病協會會員

2. 廣東省預防醫學會流行病學專業委員會青年委員會常務委員

3. 廣東省預防醫學會社會醫學與公共衛生專業委員會常務委員

4. 全國公共衛生與預防醫學名詞編寫委員會流行病學名詞編寫分委會委員

5. 廣東省新冠病毒疫苗預防接種異常反應調查診斷專家組專家


主要承擔或參與的課題

  • 國家自然科學基金青年基金. 海洋源性NA和NF-кB雙靶向抗流感新型先導化合物研究. 81201283. 23萬. 2013.1-2015.12. 主持
  • 廣東省基礎與應用基礎研究基金自然科學基金，省級科研項目, 2022A1515011012, 新冠疫苗有效性的預測評價體系建立, 2022.01-2024.12.31. 10萬元, 在研, 主持
  • 2019-nCoV感染危險因素及感染傳播途徑研究，佛山市“新型冠狀病毒感染的肺炎”應急科技攻關專項（2020001000430）200萬. (2020.6-2022.6) (Co-PI)
  • 中國博士後科學基金. 海洋源性神經氨酸酶抑制劑類化合物VD3抗流感病毒分子機制研究. 20110490954. 3萬. 2011.4-2013.3. 主持
  • 廣州市科技計劃-珠江科技新星專項. EV71手足口病重症病例的危險因素及預測模型研究. 201506010072. 30萬. 2015.1.1-2017.12.31. 主持.
  • 廣東省省級科技計劃. Global Health理念下廣東居民傳染病防控知識普及研究. 2017A070713013.10萬.2017.1.1-2018.12.31.支持.
  • 廣州市科學技術協會-科普合作與交流工程專項. 廣東在全球突發傳染病發生中的作用及公衆預防措施科技普及研究. K2016070302. 2萬. 2016.1-2016.12. 主持
  • 橫向-浙江大學. 傳染病信息平台廣東示範區數據清洗複核分析.5萬. 2015.1-2015.12.主持
  • 國家“十一五”艾滋病和病毒性肝炎等重大傳染病科技專項. 廣東省傳染病病原譜流行規律研究. 2009ZX10004213. 1539萬. 2009.1-2011.12. 主要執行人之一
  • 國家“十二五”艾滋病和病毒性肝炎等重大傳染病科技專項. 廣東省傳染病病原譜流行規律研究. 2012ZX10004213. 1570.17萬. 2012.1-2015.12. 主要執行人之一
  • “十二五”國家科技重大專項. 廣東艾滋病、病毒性肝炎社區綜合防治研究. 2012ZX10004-902. 2425.77萬. 2012.1-2015.12.主要執行者之一。主要負責生物樣本庫的建設、各家合作單位聯系協調及各種項目材料的撰寫工作。
  • “十三五”國家科技重大專項. 廣東艾滋病、病毒性肝炎和結核病社區綜合防治研究. 2018ZX10004-902. 2425.77萬. 2018.1-2020.12.主要執行者之一。主要負責生物樣本庫的建設、各家合作單位聯系協調及各種項目材料的撰寫工作。
  • 國家自然科學基金面上項目. 基于病毒樣顆粒技術的基孔肯雅病毒感染免疫機制研究. 81373050. 60萬. 2014.1-2017.12. 參與
  • 國家自然科學基金面上項目. 基于One Health理念建立動物職業暴露人群流感監測體系的研究. 81473034. 60萬. 2015.1-2018.12. 參與
  • 國家自然科學基金面上項目. 手足口病氣象、社會經濟和人口學危險因素研究.81473064. 70萬. 2015.1-2018.12. 參與

 

以第一作者或通訊作者發表文章

  1. Jiayi Zhong, Qianhong Zhong, Husheng Xiong, Dawei Wu, Caiyun Zheng, Shuang Liu, Qinyi Zhong, Yan Chen, Dingmei Zhang. Public acceptance of COVID-19 control measures and associated factors during Omicron-dominant period in China: a cross-sectional survey. BMC Public Health (2024) 24:543.
  2. Shuang Liu*, Ping Wang*, Xiaolu Shi*, Tingsong Weng, Jiayi Zhong, Xiaomin Zhang, Jing Qu, Long Chen, Qing Xu, Xiang Meng, Husheng Xiong, Dawei Wu, Dajun Fang#, Bo Peng#, Dingmei Zhang#. Maternal antibody transfer rate of vaccination against SARS-CoV-2 before or during early pregnancy and its protective effectiveness on offspring. J Med Virol. 2023;95:e29125.
  3. Yajuan Zhu*, Husheng Xiong*, Shuang Liu, Dawei Wu, Xiaomin Zhang, Xiaolu Shi , Jing Qu, Long Chen, Zheng Liu, Bo Peng#, Dingmei Zhang#. Combining MOE Bioinformatics Analysis and In Vitro Pseudovirus Neutralization Assays to Predict the Neutralizing Ability of CV30 Monoclonal Antibody on SARS-CoV-2 Variants. Viruses. 2023 Jul; 15(7): 1565.
  4. Zhu, Y.; Zhong, Q.; Ma, Z.; Liu, S.; Lan, Y.; Peng, B.; Zhang, X.; Shi, X.; Qu, J.;Wu, Z.; Zhimeng Zhao, Xilin Zhang, Dingmei Zhang. Neutralization Effect of Sera against Delta and Omicron in Patients Recovering from COVID-19 and Inactivated Vaccine Recipients. Vaccines 2023, 11, 471. 
  5. Jiayi Zhong; Wen Wang; Shuang Liu; Yifei Chen; Husheng Xiong; Xiang Meng; Dingmei Zhang; Yu Ma; Effectiveness of Matermallnactivated COvlD-19Vaccination against Omicron lnfection in infants during the First 12 Months of Life: A Test-Negative Case-Control Study, Vaccines,2023, 11(9): 1402.
  6. Zhang, D.; Zhong, J.; Xiong, H.; Li, Y.; Guo, T.; Peng, B.; Fang, C.; Kang, Y.; Tan, J.; Ma, Y. Protective Effect of Inactivated COVID-19 Vaccines against Omicron BA.2 Infection in Guangzhou: A Test-Negative Case-Control Real-World Study. Vaccines 2023, 11, 566. 
  7. Yufen Li, Tong Guo, Jiayi Zhong, Chuanjun Fang, Husheng Xiong, Zengyun Hu, Yajuan Zhu, Jinlin Tan, Shuang Liu, Qinlong Jing, Dingmei Zhang. Effect of Vaccination Time Intervals on SARS-COV-2 Omicron Variant Strain Infection in Guangzhou: A Real-World Matched Case-Control Study. Vaccines (Basel) 2022 Nov 1;10(11):1855.
  8. Lin Gan, Yan Chen, Jinlin Tan, Xuezhi Wang, Dingmei Zhang. Does potential antibody-dependent enhancement occur during SARS-CoV-2 infection after natural infection or vaccination? A meta-analysis. BMC Infect Dis. 2022 Sep 19;22(1):742. 
  9. Jinlin Tan, Zhilong Wu, Lin Gan, Qianhong Zhong, Yajuan Zhu, Yufen Li, Dingmei Zhang. Impact of Vaccination and Control Measures on the Fatality of COVID‑19: An Ecological Study. J Epidemiol Glob Health. 2022 Sep 26;1-16.
  10. Tan, J.; Wu, Z.; Hu, P.; Gan, L.; Wang, Y.; Zhang, D*. Association between Mutations in Papain-like Protease (PLpro) of SARS-CoV-2 with COVID-19 Clinical Outcomes. Pathogens 2022, 11, 1008. 
  11. Zhu, Y.; Liu, S.; Zhang, D*. Effectiveness of COVID-19 Vaccine Booster Shot Compared with Non-Booster: A Meta-Analysis. Vaccines 2022, 10, 1396. 
  12. Hongchun Du, Yajuan Zhu, Yan Chen, Shidan Zhou, Jiani Tong, Yingnan Deng, Dingmei Zhang*. Surveillance system-based physician reporting of pneumonia of unknown etiology in China: A cross-sectional study. Asian Pacific Journal of Tropical Medicine 2022; 15(4): 153-160.
  13. Shuang Liu, Jiayi Zhong and Dingmei Zhang*. Transplacental Transfer of Maternal Antibody against SARS-CoV-2 and Its Influencing Factors: A Review. Vaccines 2022, 10, 1083. 
  14. Xiao-Ning Li, Yong Huang, Wen Wang, Qin-Long Jing , Chun-Huan Zhang , Peng-Zhe Qin , Wei-Jie Guan, Lin Gan, Yi-Lan Li , Wen-Hui Liu, Hang Dong, Yu-Tian Miao, Shu-Jun Fan, Zhou-Bin Zhang*, Ding-Mei Zhang*, Nan-Shan Zhong*. Effectiveness of inactivated SARS-CoV-2 vaccines against the Delta variant infection in Guangzhou: a test-negative case-control real-world study. Emerg Microbes Infect. 2021 Dec;10(1):1751-1759.
  15. Liu J, Chen Y, Hu P, Gan L, Tan QM, Huang XQ, Ma ZZ, Lin CJ, Wu DW, Zhu X, Zhang DM*. Caregivers: the potential infection resources for the sustaining epidemic of hand, foot, and mouth disease/herpangina in Guangdong, China?[J]. Archives of Public Health.  2021 Apr 23;79(1): 54.
  16. Gan L, Chen Y, Hu P, Wu D, Zhu Y, Tan J, Li Y, Zhang D. Willingness to Receive SARS-CoV-2 Vaccination and Associated Factors among Chinese Adults: A Cross Sectional Survey[J]. International Journal of Environmental Research and Public Health,2021,18(4):1993.
  17. Hu P, Ma M, Jing Q, Ma Y, Gan L, Chen Y, Liu J, Wang D, Zhang Z, Zhang D. Retrospective study identifies infection related risk factors in close contacts during COVID-19 epidemic[J]. International Journal of Infectious Diseases,2021,103:395-401.
  18. Peipei Hu , Jundi Liu , Lin Gan, Yan Chen, Kaiyi Su, Yuxing Chen, Dingmei Zhang. Lack of Effective Home Quarantine: The Cause of the Continuing Prevalence of Hand, Foot, and Mouth Disease in China? J Infect Public Health. 2020 May 27;S1876-0341(20)30477-9.
  19. Hu P, Liu J, Zhang D. Association of NTCP Gene Polymorphisms and Spontaneous Clearance of Hepatitis B Virus in Asia: A Meta-Analysis[J]. Hepatitis Monthly,2019,19(9): e94500.
  20. Liu J, Deng Y, Jing Q, Chen X, Du Z, Liang T, Yang Z, Zhang D, Hao Y. Dengue Infection Spectrum in Guangzhou: A Cross-Sectional Seroepidemiology Study among Community Residents between 2013 and 2015. Int J Environ Res Public Health. 2018 Jun 11;15(6). pii: E1227.
  21. Jundi Liu, Xiaolu Tian, Yu Deng, Zhicheng Du, Tianzhu Liang, Yuantao Hao and Dingmei Zhang. Risk Factors Associated with Dengue Virus Infection in Guangdong Province: A Community-Based Case-Control Study. Int. J. Environ. Res. Public Health 2019, 16, 617.
  22. Dingmei Zhang. A template for EV-A71 vaccine evaluation in the real world. Lancet Child Adolesc Health. 2019 Jul 30. pii: S2352-4642(19)30181-6.
  23. Dingmei Zhang, Yan Chen, Xiashi Chen, Zhenjian He, Xun Zhu, Yuantao Hao. Enterovirus 71 Neutralizing Antibodies Seroepidemiological Research among Children in Guangzhou, China between 2014 and 2015: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2017, Mar 20, 14(3), 319.
  24. Dingmei Zhang, Ruolin Li, Wangjian Zhang, Guowei Li, Zhanzhong Ma, Xiashi Chen, Zhicheng Du, Zhiyuan Li, Pi Guo, Zhuochen Lin, Jiahai Lu, Yuantao Hao. A Case-control Study on Risk Factors for Severe Hand, Foot and Mouth Disease. Scientific Reports. 2017 Jan 13;7:40282. 
  25. Zhicheng Du, Wangjian Zhang, Dingmei Zhang, Shicheng Yu, Yuantao Hao. The threshold effects of meteorological factors on Hand, foot, and mouth disease (HFMD) in China, 2011. Scientific Reports. 2016 Nov 16;6: 36351.
  26. Pengyuan Li, Tao Li, Qiuyun Gu, Xiaomin Chen, Jiahui Li, Xiashi Chen, Yan Chen, Danwei Zhang, Rong Gao, Zhenjian He, Xun Zhu, Wangjian Zhang, Yuantao Hao, Dingmei Zhang. Children’s Caregivers and Public Playgrounds: Potential Reservoirs of Infection of Hand-foot-and mouth Disease. Scientific Reports. 2016 Nov 7;6:36375.
  27. Haogao Gu, Ross Ka-Kit Leung, Qinlong Jing, Wangjian Zhang, Zhicong Yang, Jiahai Lu, Yuantao Hao, Dingmei Zhang. Meteorological Factors for Dengue Fever Control and Prevention in South China. Int J Environ Res Public Health. 2016, Aug 31; 13(9), 867.
  28. Dingmei Zhang, Zhiyuan Li, Wangjian Zhang, Pi Guo, Zhanzhong Ma, Qian Chen, Shaokun Du, Jing Peng, Yu Deng and Yuantao Hao. Hand-Washing: The Main Strategy for Avoiding Hand, Foot and Mouth Disease. Int J Environ Res Public Health. 2016 Jun 18;13(6). pii: E610.
  29. Dingmei Zhang*, Mengmeng Ma*, Weitao Wen*, Xun Zhu, Lin Xu, Zhenjian He, Xia He, Jueheng Wu, Yiwen Hu, Yun Zheng, Yu Deng,  Cuiji Lin, Jiahai Lu, Mengfeng Li, Kaiyuan Cao. Clinical epidemiology and molecular profiling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou, China. Epidemiology and Infection. 2015 Aug;143(11):2315-29.
  30. Dingmei Zhang*, Zhenjian He*, Lin Xu*, Xun Zhu, Jueheng Wu, Weitao Wen, Yun Zheng, Yu Deng, Jieling Chen, Yiwen Hu, Mengfeng Li, Kaiyuan Cao. Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in Southern China. International Journal of Infectious Diseases, 2014,Aug;25:159-64. doi: 10.1016/j.ijid.2014.02.019.
  31. Jing Peng, Dingmei Zhang#, Yu Ma, Guoling Wang, Zhongmin Guo, Jiahai Lu#. Protective effect of fluvastatin on influenza virus infection. Molecular Medicine Reports. 2014 Jun;9(6):2221-6.
  32. Lin Xu*, Xia He*, Dingmei Zhang*, Zhu Wang, Fashen Feng, Yang Wang, Mengfeng Li, Kaiyuan Cao. Surveillance and gene analysis of Human Bocavirus in patients with respiratory infection in Guangzhou, China. Plos One, 2012;7(9):e44876.
  33. Dingmei Zhang, Jiahai Lu. Enterovirus 71 (EV71) vaccine: close but still far. International Journal of Infectious Diseases, 2010, 14(9):e739-43.
  34. Dingmei Zhang, Jiahai Lu, Nanshan Zhong. Pathogenesis of severe acute respiratory syndrome. Chinese medical journal 2008, 121(17):1722-1731.
  35. Dingmei Zhang, Guoling Wang, Jiahai Lu. Severe acute respiratory syndrome: vaccine on the way. Chinese medical journal 2005, 118(17):1468-1476. 
  36. Jiahai Lu*, Dingmei Zhang*, Guoling Wang*, Zhongmin Guo*, Bingyan Tan, Liping Ouyang, Li Lin, Yimin Liu, Weiqing Chen, Wenhua Ling, Xinbing Yu, Nanshan Zhong. Variation analysis of the severe acute respiratory syndrome coronavirus putative non-structural protein 2 gene and construction of three-dimensional model. Chinese medical journal 2005, 118(9):707-713.
  37. Jiahai Lu*, Dingmei Zhang*, Guoling Wang*, Zhongmin Guo*, Juan Li*, Bingyan Tan, Liping Ou-Yang, Wenhua Ling, Xinbing Yu, Nanshan Zhong. Sequence analysis and structural prediction of the severe acute respiratory syndrome coronavirus nsp5. Acta biochimica biophysica Sinica 2005, 37(7):473-479.
  38. 張定梅，朱勳，姚婷婷，徐霖，吳珏珩，何振健，鄭芸，曹開源. 廣東省2009-2012年呼吸道合胞病毒的流行病學特征.太阳集团app首页學報（醫學科學版）2013.3.34(2):292-8
  39. 李鵬媛，徐浩，顧豪高，馬蒙蒙，陸家海，郝元濤，張定梅. 中國大陸H7N9禽流感病毒流行病學特征及血凝素和神經氨酸酶的分子進化研究. 太阳集团app首页學報（醫學科學版）. 2014.11.35(6):932-940.
  40. 顧豪高，張王劍，徐浩，李鵬媛，吳洛林，郭貔，郝元濤，陸家海，張定梅. 中國人感染H7N9 禽流感危險區域預警識别的研究. 中華流行病學雜志. 2015, 36 (5): 470-475. 
  41. 李鵬媛，劉佑瓊，張定梅.埃博拉病毒及埃博拉出血熱. 中國預防醫學雜志. 2015,16(8):632-637.

 

參編教材：

1.《影響人類健康的常見人獸共患病》，太阳集团app首页出版社，2009年，副主編

2.《悄然的拜訪者-大衆傳染病防控》，太阳集团app首页出版社，2019年，主編