【職  稱】 教授(博士生導師) 

【所屬部門】 勞動衛生與環境衛生學系

【電子郵件】zxw63@mail.sysu.edu.cn

【研究方向】環境流行病學、環境毒理學

【研究生招生專業】勞動衛生與環境衛生學、公共衛生碩士(MPH)

 

【學術簡曆】


        太阳集团1088vip,教授/博士生導師,勞動衛生與環境衛生學系主任,教育部“環境與健康國際合作聯合實驗室”副主任。入選國家高層次人才特殊支持計劃青年拔尖人才,廣東省傑出青年科學基金獲得者。主要研究方向為環境污染物的生物監測及健康風險研究,重點關注大氣超細顆粒物和新污染物暴露的健康效應及分子機制。目前已主持國家重點研發計劃國際合作項目和國家自然科學基金等十餘項省部級以上項目。目前以第一作者/通訊(含并列)作者發表SCI論文50餘篇;參編5本專著/教材;目前擔任廣東省環境誘變劑學會秘書長。

 

【教育經曆】


2003/09-2009/12,太阳集团app首页,環境科學與工程學院,環境科學,博士(導師:仇榮亮教授)

2007/04-2008/08,美國佛羅裡達大學,食品與農業學院,國家留學基金委博士生聯合培養(導師:Lena Ma教授)

1999/09-2003/06,河南大學,環境與規劃學院 ,資源環境與城鄉規劃管理,本科

 

【研究工作經曆】


2021/02       至今,太阳集团app首页,太阳集团1088vip,教授/博導

2018/12-2019/12,澳大利亞墨爾本大學,訪問學者

2015/01-2021/01,太阳集团app首页,太阳集团1088vip,副教授/博導

2012/07-2015/01,太阳集团app首页,太阳集团1088vip,講師/碩導

2010/07-2012/06,太阳集团app首页,太阳集团1088vip,師資博士後(導師:陳雯教授)

2010/01-2010/06,太阳集团app首页,廣東省環境污染控制與修複技術重點實驗室,科研助理

 

【主要社會兼職】


  1. 廣東省環境誘變劑學會,秘書長
  2. 中國環境科學學會環境醫學與健康分會,委員
  3. 中國環境誘變劑學會環境表觀遺傳專委會,委員                  
  4. 中國環境誘變劑學會環境流行病學專委會,委員
  5. 廣東省毒理學會,常務理事

 

【主要承擔的課題】


1.國家重點研發計劃項目課題:PFAS和抗生素類新污染物人體健康危害與生态毒性表征(主持,2024.12-2027.11)

2.國家重點研發計劃國際創新合作重點專項:交通源超細顆粒物暴露與神經退行性疾病風險評估的關鍵技術及應用(主持,2019.08-2022.12)

3.國家自然科學基金面上項目:新興全氟化合物替代品早期暴露對子代神經發育的影響及脂質代謝的作用機制(主持,2021.01-2024.12)

4.國家自然科學基金面上項目:生命早期全氟化學物暴露影響兒童疫苗接種免疫應答的機制(主持,2017.01-2020.12)

5.國家自然科學基金青年項目:鋅镉處理下超富集植物的差異蛋白質表達及金屬耐性機理研究(主持,2011.01-2013.12)

6.廣東省自然科學基金傑出青年項目:大氣超細顆粒物的神經毒性及脂質代謝介導的作用機制(主持,2021.01-2024.12

7.廣東省自然科學基金面上項目:基于暴露組學的環境污染物緻新生兒不良出生結局的隊列研究(主持,2016.06-2019.06)

8.有機地球化學國家重點實驗室開放基金:全氟化學物暴露與新生兒不良出生結局及全基因組DNA甲基化的相關性研究(主持,2017.01-2018.12)

9.廣州市科技計劃科技菁英“領航”項目:新興全氟化合物替代品的子代神經毒性及暴露風險評估(主持,2024.01-2026.12)

10.中央高校青年教師重點培育項目:胎兒宮内生長受限與兒童早期神經認知功能的相關性——基于生命早期環境污染物暴露與不良出生結局的隊列研究(主持,2017.01-2018.12)

11.中國博士後基金第四批特别資助項目:microRNA調控苯代謝關鍵酶表達及其效應研究(主持,2011-2013)

12.中國博士後科學基金第48批資助項目:電子廢棄物處置區域的環境特征污染物與人體健康損傷(主持,2010-2012)

 

【近五年主要論著】#并列第一作者,*通訊作者


 

  1. Cai D#, Li SP#, Guo YT, Chou WC, Mohammed Z, Qiu RL, Hu G, Qi J, Ren M, Xiang M, Li Z, Zhou Y, Huang J, Kong M, Xie Y, Tang C, Lin LZ, Yu Y*, Dong GH*, Zeng XW*. Effects of serum insulin and insulin-like growth factor 1 levels on the association between fetal growth and per- and polyfluoroalkyl substance exposure based on a nested case-control study. Environmental Science & Technology. 2025. doi.org/10.1021/acs.est.4c08752.
  2. Li SP, Zhao WH, Zhang J, Jiang WT, Zhu JY, Luo YX, Xiang P, Bloom M, Jalava P, Gong GH,  Zeng XW*. Effects of early-life F-53B exposure on thyroid function in juvenile rats: The role of the cAMP signaling pathway. Journal of Hazardous Materials. 2025. 489:137751.
  3. Zeng HX, Qin SJ, Wu QZ, Zeng QG, Li JH, Oudin A, Kannien KM, Yang M, Jalava P, Dong GH, Zeng XW*. Circular RNA circ_0061183 regulates microglial polarization induced by airborne ultrafine particles in HMC3 cells via sponging miR-98-5p. Journal of Hazardous Materials. 2025. 484:136724.
  4. Li JH#, Zeng HX#, Wei J, Wu QZ, Qin SJ, Zeng QG, Zhao B, Dong GH, Shen JC*, Zeng XW*. Long-term exposure to PM2.5 and its constituents and visual impairment in schoolchildren: A population-based survey in Guangdong province, China. Environment International. 2025.195: 109270.
  5. Qin SJ, Zeng QG, Zeng HX, Meng WJ, Wu QZ, Lv Y, Dai J, Dong GH, Zeng XW*. Novel perspective on particulate matter and Alzheimer's disease: Insights from adverse outcome pathway framework. Environmental Pollution. 2025. 367:125601.
  6. Zeng HX, Qin SJ, Andersson J, Li SP, Zeng QG, Li JH, Wu QZ, Oudin A, Kannien KM, Jalava P, Dong GH, Zeng XW*. The emerging role of particulate matter-changed non-coding RNAs in the pathogenesis of Alzheimer's disease: A comprehensive in silico analysis and review. Environmental Pollution. 2025. 366:125440.
  7. Zhang J, Li SP, Li QQ, Zhang YT, Dong GH, Canchola A, Zeng XW*, Chou WC*. Development of a physiologically based pharmacokinetic (PBPK) model for F-53B in pregnant mice and its extrapolation to humans. Environmental Science & Technology. 2024. 58:18928.
  8. Wu QZ, Zeng HX, Andersson J, Oudin A, Kanninen KM, Xu MW, Qin SJ, Zeng QG, Zhao B, Zheng M, Jin N, Chou WC, Jalava P, Dong GH, Zeng XW*. Long-term exposure to major constituents of fine particulate matter and neurodegenerative diseases: A population-based survey in the Pearl River Delta Region, China. Journal of Hazardous Materials. 2024. 470:134161.
  9. Qin SJ, Zeng QG, Zeng HX, Li SP,  Andersson J, Zhao B, Oudin A, Kannien KM, Jalava P, Jin NX, Yang M, Lin LZ, Liu RQ, Dong GH, Zeng XW*. Neurotoxicity of fine and ultrafine particulate matter: A comprehensive review using a toxicity pathway-oriented adverse outcome pathway framework. Science of the Total Environment. 2024.947:174450.
  10. Li SP, Zeng HX, Qin SJ, Li QQ, Wu LY, Wu QZ,. Lin LZ, Dong GH, Zeng XW*. Effects on synaptic plasticity markers in fetal mice and HT22 neurons upon F-53B exposure: the role of PKA cytoplasmic retention. Environmental & Health (Wash). 2024. 2:776.
  11. Li SP, Qin SJ, Zeng HX, Chou WC, Oudin A, Kannien KM, Jalava P, Dong, Zeng XW*. Adverse outcome pathway for the neurotoxicity of per- and polyfluoroalkyl substances: A systematic review. Eco-Environment & Health. 2024. 3:476.
  12. Guo YT#, Huang JB#, Xue JC, Qin SJ, Cai D, Wu QZ, Chu C, Tang C, Xie Y,Lin LZ, Dong GH, Zeng XW*. Intrauterine exposure to long-chain perfluorocarboxylic acids (PFCAs) were associated with reduced primary bile aci8des in three-year-old children: Finding from a prospective birth cohort study. Environmental Pollution. 2024. 360:124583.
  13. Li SP#, Wu LY#, Zeng HX, Zhang J, Qin SJ, Liang LX, Andersson J, Meng WJ, Chen XY, Wu QZ, Lin LZ, Chou WC, Dong GH. Zeng XW*. Hepatic injury and ileitis associated with gut microbiota dysbiosis in mice upon F-53B exposure. Environmental Research. 2024. 248:118305.
  14. Yang M, Wu QZ, Zhang YT, Leskinen A, Wang XF, Komppula M, Hakkarainen H, Roponen M, Jin NX, Tan WH, Xu SL, Lin LZ, Liu RQ, Zeng XW*, Dong GH*. Toxicological evaluation and concentration of airborne PM0.1 in high air pollution period in Guangzhou, China. Science of the Total Environment. 2024.921:171224. 
  15. Qin XD#, Zhou Y#, Bloom B#, Qian Z, Geiger SD, Vaughn MG, Chu C, Li QQ, Yang BY, Hu LW, Yu Y,  Zeng XW*, Dong GH*. Prenatal exposure to PFAS, associations with preterm birth and modification by maternal estrogen levels: The Maoming birth study. Environmental Health Perspectives. 2023.131:117006.
  16. Zeng XW#, Bloom M#, Wei F#, Liu L, Qin J, Xue L, Wang S, Huang G, Teng M, He B, Mao X, Chu C, Lin S*, Dong GH*, Tan W*. Perfluoroalkyl acids in follicular fluid and embryo quality during IVF: a prospective IVF cohort in China. Environmental Health Perspectives. 2023.131:27002.

  17. Zhang YT#, Bao H#, Zhang L#, Wen S, Tan W, Zeeshan M, Sun MK, Chu C, Gui ZH, Lin LZ, Liu RQ, Zeng XW*, Yu Y*, Dong GH*. Health risk assessment of perfluorooctane sulfonate and perfluorooctanoic acid exposure in China based on epidemiological data. Hygiene and Environmental Health Advances. 2023. 7: 100066.

  18. Li QQ#, Huang J#, Cai D#, Chou WC, Zeeshan M, Chu C, Zhou Y, Lin L, Ma H, Xie Y, Dong GH*, Zeng XW*. Prenatal exposure to legacy and alternative PFAS and neuropsychological development trajectories over the first three years of life. Environmental Science & Technology. 2023. 57: 3746.

  19. Yang M#, Wu QZ#, Zhang YT, Leskinen A, Komppula M, Hakkarainen H, Roponen M, Xu SL, Lin LZ, Liu RQ, Hu LW, Yang BY, Zeng XW*, Dong GH*, Jalava P. Concentration, chemical composition and toxicological responses of the ultrafine fraction of urban air particles in PM1. Environment International. 2022.170: 107661.

  20. Li QQ#, Liu JJ#, Su F, Zhang YT, Wu LY, Chu C, Zhou YZ, Shen X, Xiong S, Geiger SD,  Qian ZM, McMillin SE, Dong GH, Zeng XW*. Chlorinated polyfluorinated ether sulfonates and thyroid hormone levels in adults: Isomers of C8 Health Project in China. Environmental Science & Technology. 2022.56:6152.

  21. Liu JJ#, Cui XX#, Tan YW#, Dong PX, Ou YQ, Li QQ, Chu C, Wu LY, Liang LX, Qin SJ, Zeeshan M, Zhou Y, Hu LW, Liu RQ, Zeng XW*, Dong GH*, Zhao XM*. Per- and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China. Environment International. 2022.163:107179.

  22. Lin LZ#, Zeng XW#, Deb B, Tabet M, Xu SL, Wu QZ, Zhou Y, Ma HM, Chen DH, Chen GB, Yu HY, Yang BY, Hu Q, Yu YJ, Dong GH, Hu LW*. Outdoor light at night, overweight, and obesity in school-aged children and adolescents. Environmental Pollution. 2022.305:119306.

  23. Wu QZ, Xu SL, Tan YW, Qian Z, Vaughn MG, McMillin SE, Dong P, Qin SJ, Liang LX, Lin LZ, Liu RQ, Yang BY, Chen GB, Zhang WJ, Hu LW, Zeng XW*, Dong GH*. Exposure to ultrafine particles and childhood obesity: A cross-sectional analysis of the Seven Northeast Cities (SNEC) Study in China. Science of the Total Environment. 2022.846:157524.

  24. Su F, Zeeshan M, Xiong LH, Lv JY, Wu Y, Tang XJ, Zhou Y, Ou YQ, Huang WZ, Feng WR*, Zeng XW*, Dong GH*. Co-exposure to perfluoroalkyl acids and heavy metals mixtures associated with impaired kidney function in adults: A community-based population study in China. Science of the Total Environment. 2022.839:156299.

  25. Zeng XW, Lodge CJ, Lowe AJ, Guo Y, Abramson M, Bowatte G, Hu LW, Yang BY, Chen ZX*, Dharmage SC*, Dong GH*. Current pet ownership modifies the adverse association between long-term ambient air pollution exposure and childhood asthma. Clinical and Translational Allergy. 2021.11:e12005.

  26. Ye WL#, Chen ZX#, Xie YQ#, Kong ML#, Li QQ, Yu S, Chu C, Dong GH, Zeng XW*. Associations between serum isomers of perfluoroalkyl acids and metabolic syndrome in adults: Isomers of C8 Health Project in China. Environmental Research. 2021.196.110430.

  27. Ou Y#, Zeng XW#, Lin S*, Bloom MS, Han F, Xiao X, Wang H, Matala R, Li X, Qu Y, Nie Z, Dong GH*, Liu X*. Gestational exposure to perfluoroalkyl substances and congenital heart defects: A nested case-control pilot study. Environment International.  2021.154:106567.

  28. Zeng XW, Lowe AJ, Lodge CJ, Heinrich J, Roponen M, Jalava P, Guo Y, Hu LW, Yang BY, Dharmage SC, Dong GH*. Greenness surrounding schools is associated with lower risk of asthma in schoolchildren. Environment International. 2020. 143:105967.

  29. Zeng XW, Li QQ, Chu C, Ye WL, Yu S, Ma HM, Zeng XY, Zhou Y, Yu HY, Hu LW, Yang BY, Dong GH*. Alternatives of perfluoroalkyl acids and hepatitis B virus surface antibody in adults: Isomers of C8 Health Project in China. Environmental Pollution. 2020. 259: 113857.

  30. Cai D#, Li QQ#, Chu C, Wang SZ, Tang YT, Appleton AA, Qiu RL, Yang BY, Hu LW, Dong GH, Zeng XW*, High trans-placental transfer of perfluoroalkyl substances alternatives in the matched maternal-cord blood serum: Evidence from a birth cohort study. Science of the Total Environment. 2020. 705: 135885.

  31. Li J#, Cai D#, Chu C, Li QQ, Zhou Y, Hu LW, Yang BY, Dong GH, Zeng XW*, Chen D*. Transplacental transfer of per- and polyfluoroalkyl substances (PFASs): Differences between preterm and full-term deliveries and associations with placental transporter mRNA expression. Environmental Science & Technology. 2020.54:5062.

  32. Wu QZ#, Li S#, Yang BY#, Bloom M#, Shi Z, Knibbs L, Dharmage S, c, Jalaludin B, Jalava P, Ropenen M, Lin S, Chen G, Guo Y, Xu SL, Yu HY, Zeeshan M, Hu LW, Yu Y*, Zeng XW*, Dong GH*. Ambient airborne particulates of diameter ≤1 μm, a leading contributor to the association between ambient airborne particulates of diameter ≤2.5 μm and children’s blood pressure. Hypertension. 2020.75:347. 

 

【書稿專著】


  1. 第二主編, 《現代環境流行病學》,科學出版社,2023年.
  2. 第一主編,《環境衛生學思政案例集》,太阳集团app首页出版社,2023年.
  3. 編委,《預防醫學》課程思政案例庫,人民衛生出版社,2024年.
  4. 第三副主編, 《空氣顆粒物與健康》,“十三五”國家重點出版物,湖北科學技術出版社,2019年.
  5. 編委,《環境與健康》,科學出版社“十四五”普通高等教育研究生規劃教材,2024年.
  6. 參編,《Ambient Air Pollution and Health Impact in China》, Springer Nature出版,2017年.

 

【學術科研獎勵】


  1. 國家高層次人才特殊支持計劃青年拔尖人才2021年

  2. 太阳集团app首页“逸仙學者”優秀學者2021年

  3. 中華醫學科技獎,三等獎(2/8)

  4. 2019年度華夏醫學科技獎,三等獎(5/6)
  5. 2018年度廣東省自然科學獎,二等獎(5/8)
  6. 2018年度廣東省環境保護科學技術獎,一等獎(10/15)
  7. 2016年度“廣東特支計劃” 百千萬工程青年拔尖人才
  8. 2011年度“太阳集团app首页優秀博士後”

 

【博士後/專職研究人員招聘】


        常年招聘從事環境毒理學、環境化學、環境流行病學、環境科學或生物信息學等領域的博士後和專職科研人員,工資26-40萬,有校内公寓,享有正式編制職工醫療、子女入學等福利待遇。優秀者在聘期結束或聘期内可直接申請學校的教授/副教授職位,歡迎各位有志于投身環境健康研究領域的青年才俊加入課題組!