一、學術簡曆
【學習經曆】
香港大學:公共衛生學、流行病學雙碩士學位、流行病學博士學位
太阳集团app首页:醫學學士學位
【工作經曆】
2016~至今 太阳集团app首页 太阳集团1088vip 教授、博士生導師
2024~至今 香港大學 榮譽教授,博士生聯合導師
2022~2024 英國伯明翰大學 榮譽高級研究員
2021~2023 香港大學 榮譽副教授,博士生聯合導師
2015~2020 香港大學 研究助理教授,博士生聯合導師
2012~2015 香港大學 太阳集团1088vip 博士後
二、社會兼職
國際流行病學期刊(IJE)編委
中華預防醫學會流行病學分會青年委員會委員
廣東省預防醫學會流行病學專業委員會委員
廣東省營養學會營養與慢病管理專業委員會委員
廣東省康複醫學會腦卒中康複專業委員會副主任委員
擔任了多份重要國際醫學期刊的審稿人,包括 Nature, Nature Communication, Lancet Diabetes & Endocrinology, BMJ, JAMA, Nature medicine等等。
三、主要承擔或參與的課題
- 國家自然科學基金面上項目,82373661,ANGPTLs基因及其蛋白表達水平調控内髒脂肪組織影響健康衰老表型的前瞻性隊列研究,2024/01~2027/12,49萬元,主持
- 國家自然科學基金(“長壽重要相關因素及其作用機制研究”專項項目),81941019,基于遺傳和環境多維度構建和驗證健康衰老表型預測模型的隊列研究,2020/01~2022/12,90萬元,已結題,主持
- 廣東省青少年重點人群關愛項目,學校體育美育衛生國防教育改革發展方案咨詢,2022年至今,合計110萬,在研,主持
- 基于大灣區Biobank隊列人群代謝衰老新型标志物探究,2024年至今,120萬,在研,主持
- 美國中華醫學基金會公開競争項目,Grant No. 24-556,整合CardioCare:在體檢中心推進心血管疾病篩查後的管理,2025/01~2027/12,10萬美元
- 國家“十三五”科技重大專項課題(增補課題),2018ZX10715004-003-003,乙肝及肝癌診斷及監測新型血清标記物在慢性HBV患者中的推廣應用研究,2019/01-2020/12,211.01萬元,已結題,(增補課題)負責人
- 廣東省自然科學基金,2018A030313140,血睾酮與缺血性心髒病:結合孟德爾随機化分析的人群前瞻性隊列研究,2018/01-2020/12,10萬,結題,主持
- 香港健康醫學研究基金(HMRF),13143241,A prospective study of Southern Chinese dietary pattern, foods and nutrients with cardiovascular disease mortality(中文題目:南中國膳食模式、食物及營養素對心血管疾病及死亡的前瞻性隊列研究,2016/04-2017/03, 53萬港币,已結題,主持
- 香港大學研究資助基金,201510159006,Establishment of cardiovascular risk prediction score in middle-age to older Chinese people(中文題目:建立中老年人心血管疾病的預測公式),2016/01-2016/12, 15.0萬港币,已結題,主持
- 香港健康醫學研究基金(HMRF),12133631,Do common liver virus infections(HAV, HBV and HCV) contribute to high diabetes risk in China?(中文題目:常見肝病毒感染是否可引起中國高糖尿病患病率?),2014/04-2015/03, 70.1萬港币,已結題,主持
- 香港大學研究資助基金,201309176086, Progression of carotid intima-media thickness and related cardiovascular outcomes in older Chinese people (中文題目:頸脈内膜-中層厚度的進展對心血管事件發生的影響),2014/01-2014/12, 5.23萬港币,已結題,主持
四、近期發表的主要文章:近10年以第一/通訊作者發表SCI論文超過 110 篇。部分代表性論著如下:
(1). Wang J, Li YR, Jiang CQ, Zhang WS, Zhu T, Zhu F, Jin YL, Lam TH, Cheng KK, Xu L(*). Chronotype and cognitive function: Observational study and bidirectional Mendelian randomization. eClinicalMedicine 2022:101713 doi: https://doi.org/10.1016/j.eclinm.2022.101713
(2). Wang J, Zhang WS(*), Jiang CQ, Zhu F, Jin YL, Cheng KK, Lam TH, Xu L(*): Associations of face-to-face and non-face-to-face social isolation with all-cause and cause-specific mortality: 13-year follow-up of the Guangzhou Biobank Cohort study. BMC Med 2022, 20(1):178.
(3). Tian WB, Zhang WS, Jiang CQ, Liu XY, Jin YL, Lam TH, Cheng KK, Xu L(*): Aortic arch calcification and risk of all-cause mortality and cardiovascular disease: The Guangzhou Biobank Cohort Study. The Lancet regional health Western Pacific 2022, 23:100460.
(4). Li MJ, Ren J, Zhang WS, Jiang CQ, Jin YL, Lam TH, Cheng KK, Thomas GN, Xu L(*): Association of alcohol drinking with incident type 2 diabetes and pre-diabetes: The Guangzhou Biobank Cohort Study. Diabetes Metab Res Rev 2022:e3548.
(5). Sun C (#), Li K (#), Xu H (#), Wang X, Qin P, Wang S, Liang B(*), Xu L(*). Association of healthy lifestyle score with all-cause mortality and life expectancy: a city-wide prospective cohort study of cancer survivors. BMC Med. 2021 Jul 7;19(1):158. doi: 10.1186/s12916-021-02024-2.
(6). Huang YY, Jiang CQ, Zhang WS(*), Zhu F, Jin YL, Cheng KK, Lam TH, Xu L(*) Mortality related to changes in physical activity in middle-aged to older Chinese: an 8-year follow-up of the Guangzhou Biobank Cohort Study. Journal of Sport and Health Science. 2021 Jul 1;10(4):430-8.
(7). Cai Q (#), Chen F (#), Wang T, Luo F, Liu X, Wu Q, He Q, Wang Z, Liu Y, Liu L, Chen J(*) and Xu L(*). Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China. Diabetes Care. 2020;43:1392-1398. [Highly Cited Papers]
(8). Cai Q (#), Huang D (#), Yu H, Zhu Z, Xia Z, Su Y, Li Z, Zhou G, Gou J, Qu J, Sun Y, Liu Y, He Q, Chen J(*), Liu L(*) and Xu L(*). COVID-19: Abnormal liver function tests. Journal of Hepatology. 2020;73:566-74. [Highly Cited Papers]
(9). Wang XJ, Jiang CQ(*), Zhang WS, Zhu F, Jin YL, Woo J, Cheng KK, Lam TH(*), Xu L(*). Milk consumption and risk of mortality from all-cause, cardiovascular disease and cancer in older people. Clinical Nutrition. 2020;39:3442-51.
(10). Jiang CQ, Xu L(*), Lam TH(*), Jin YL, Sen Zhang W, Zhu F, Thomas GN and Cheng KK. Glycaemic measures and risk of mortality in older Chinese: the Guangzhou Biobank Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 2019; 105(3): e181–190. doi: 10.1210/clinem/dgz173.
(11). Ma XQ, Jiang CQ(*), Xu L(*), Zhang WS, Zhu F, Jin YL, Thomas GN and Lam TH. Sleep quality and cognitive impairment in older Chinese: Guangzhou Biobank Cohort Study. Age Ageing. 2019;49(1):119-124. doi: 10.1093/ageing/afz120.
(12). Xu L, Borges MC, Hemani G, Lawlor DA. The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study. Diabetologia. 2017;60(11):2210-2220.
(13). Xu L, Jiang CQ, Lam TH, Zhang WS, Zhu F, Jin YL, Thomas GN, Cheng KK and Schooling CM. Mendelian randomization estimates of alanine aminotransferase with cardiovascular disease: Guangzhou Biobank Cohort study. Hum Mol Genet. 2017;26:430-437.
(14). Xu L, Lam TH, Jiang CQ., Zhang WS, Jin YL, Zhu T, Thomas GN, Cheng KK. Changes in adiposity in an older Chinese population in rapid economic transition. Obesity, 2016;24(10), 2217-2223.
(15). Lam TH(#), Xu L(#), Schooling CM(*), Chan WM, Lee SY, Leung GM. Smoking and mortality in a prospective cohort study of older chinese in Hong Kong. Addiction. 2015;110(3):502-510.
(16). Xu L, Jiang CQ, Lam TH(*), Zhang WS, Cherny SS, Thomas GN, Cheng KK. Sleep duration and memory in the elderly chinese: Longitudinal analysis of the Guangzhou Biobank Cohort Study. Sleep. 2014;37:1737-1744
(17). Xu L, Freeman G, Cowling BJ, Schooling CM(*). Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials. BMC Medicine. 2013;11:108. [Highly Cited Papers]
(18). Xu L, Schooling CM(*), Chan WM, Lee SY, Leung GM, Lam TH. Smoking and hemorrhagic stroke mortality in a prospective cohort study of older Chinese. Stroke. 2013;44(8):2144-2149.
(19). Xu L, Jiang CQ, Lam TH(*), Liu B, Jin YL, Zhu T, Zhang WS, Cheng KK and Thomas GN. Short or long sleep duration is associated with memory impairment in older Chinese: the Guangzhou Biobank Cohort Study. Sleep 2011;34(5):575-80.
(20). Xu L, Jiang CQ, Lam TH(*), Cheng KK, Yue XJ, Lin JM, Zhang WS and Thomas GN. Impact of impaired fasting glucose and impaired glucose tolerance on arterial stiffness in an older Chinese population: the Guangzhou Biobank Cohort Study-CVD. Metabolism 2010;59(3):367-72.
(21). Xu L, Jiang CQ, Lam TH(*), Yue XJ, Cheng KK, Liu B, Jin YL, Zhang WS and Thomas GN. Brachial-ankle pulse wave velocity and cardiovascular risk factors in the non-diabetic and newly diagnosed diabetic Chinese: Guangzhou Biobank Cohort Study-CVD. Diabetes Metabolism Research & Review 2010;26(2):133-9.
五、研究生培養情況: 自2012年以來平均每年培養3-6名碩士研究生,自2015年以來擔任香港大學博士生聯合導師,2016年以來擔任太阳集团app首页博士生導師,2020年以來擔任英國伯明翰大學研究生聯合導師
六、招生專業: 慢性病流行病學
七、獲獎情況
- 2008 獲賀達理教授獎(Professor Anthony Hedley Prize for Master of Public Health), 香港大學(年級總分第一名,優秀畢業論文獎)
- 2011獲龍榮軾教授及朱淑濂女士研究生獎學金(YS and Christabel Lung Postgraduate Scholarship), 香港大學
- 2011年參與項目《廣州生物庫中老年隊列的建立與常見慢性重大疾病的相關因素研究》,研究團隊獲中華預防醫學會科學進步獎二等獎
- 2012再次獲龍榮軾教授及朱淑濂女士研究生獎學金(YS and Christabel Lung Postgraduate Scholarship), 香港大學
- 2014年參與項目《廣州生物庫中老年隊列的建立與常見慢性重大疾病的相關因素研究》,研究團隊獲廣東省科學技術進步獎二等獎
- 2015年獲香港大學/美國中華醫學基金會(University of Hong Kong/China Medical Board)聯合基金資助